MicroRNA-1/133 targeted dysfunction of potassium channels KCNE1 and KCNQ1 in human cardiac progenitor cells with simulated hyperglycemia.

Li, Yangxin; Yang, Chen-Min; Xi, Yutao; Wu, Geru; Shelat, Harnath; Gao, Song; Cheng, Jie; Geng, Yong-Jian

Li, Yangxin; Yang, Chen-Min; Xi, Yutao; Wu, Geru; Shelat, Harnath; Gao, Song; Cheng, Jie; Geng, Yong-Jian.

Int J Cardiol ; 167(3): 1076-8, 2013 Aug 10.

Article in En | MEDLINE | ID: mdl-23157812

Subject(s)

Hyperglycemia/metabolism; KCNQ1 Potassium Channel/antagonists & inhibitors; MicroRNAs/toxicity; Myocytes, Cardiac/metabolism; Potassium Channels, Voltage-Gated/antagonists & inhibitors; Stem Cells/metabolism; Glucose/toxicity; Humans; Hyperglycemia/chemically induced; KCNQ1 Potassium Channel/physiology; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/pathology; Potassium Channels, Voltage-Gated/physiology; Stem Cells/drug effects; Stem Cells/pathology

Key words

Arrhythmias; Cardiac progenitor cells; Diabetes; MicroRNA; Potassium channel

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Potassium Channels, Voltage-Gated / Myocytes, Cardiac / MicroRNAs / KCNQ1 Potassium Channel / Hyperglycemia Limits: Humans Language: En Journal: Int J Cardiol Year: 2013 Document type: Article Country of publication: Netherlands

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