Monosomy 3 and isochromosome 8q in a uveal melanoma.
Cancer Genet Cytogenet
; 45(2): 249-53, 1990 Apr.
Article
in En
| MEDLINE
| ID: mdl-2317773
ABSTRACT
Chromosome analysis of a locally invasive uveal melanoma revealed monosomy 3 and i(8q). Sublines with multiple copies of the i(8q) were also present. Loss of heterozygosity for genes on chromosome 3 and duplication of genes on 8q may play an important role in progression of uveal melanoma.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uveal Neoplasms
/
Chromosomes, Human, Pair 3
/
Chromosomes, Human, Pair 8
/
Chromosome Aberrations
/
Chromosome Deletion
/
Melanoma
/
Monosomy
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Cancer Genet Cytogenet
Year:
1990
Document type:
Article
Affiliation country:
Canada