Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

El-Kordi, Ahmed; Winkler, Daniela; Hammerschmidt, Kurt; Kästner, Anne; Krueger, Dilja; Ronnenberg, Anja; Ritter, Caroline; Jatho, Jasmin; Radyushkin, Konstantin; Bourgeron, Thomas; Fischer, Julia; Brose, Nils; Ehrenreich, Hannelore

El-Kordi, Ahmed; Winkler, Daniela; Hammerschmidt, Kurt; Kästner, Anne; Krueger, Dilja; Ronnenberg, Anja; Ritter, Caroline; Jatho, Jasmin; Radyushkin, Konstantin; Bourgeron, Thomas; Fischer, Julia; Brose, Nils; Ehrenreich, Hannelore.

Affiliation

El-Kordi A; Division of Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

Behav Brain Res ; 251: 41-9, 2013 Aug 15.

Article in En | MEDLINE | ID: mdl-23183221

Subject(s)

Autistic Disorder/genetics; Behavior, Animal/physiology; Carrier Proteins/genetics; Membrane Proteins/genetics; Social Behavior; Vocalization, Animal/physiology; Animals; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Female; Genetic Predisposition to Disease; Grooming/physiology; Male; Mice; Mice, Knockout; Phenotype; Severity of Illness Index; Sex Characteristics; Stereotyped Behavior/physiology

Key words

ASD; Gender differences; Grooming; Nest building; Repetitive behaviors; Social interaction; Stereotypies; Ultra-sound vocalization

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Social Behavior / Vocalization, Animal / Behavior, Animal / Carrier Proteins / Membrane Proteins Type of study: Prognostic_studies Aspects: Determinantes_sociais_saude Limits: Animals Language: En Journal: Behav Brain Res Year: 2013 Document type: Article Affiliation country: Germany

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