Mast cells protect from post-traumatic brain inflammation by the mast cell-specific chymase mouse mast cell protease-4.

Hendrix, Sven; Kramer, Peter; Pehl, Debora; Warnke, Katharina; Boato, Francesco; Nelissen, Sofie; Lemmens, Evi; Pejler, Gunnar; Metz, Martin; Siebenhaar, Frank; Maurer, Marcus

Hendrix, Sven; Kramer, Peter; Pehl, Debora; Warnke, Katharina; Boato, Francesco; Nelissen, Sofie; Lemmens, Evi; Pejler, Gunnar; Metz, Martin; Siebenhaar, Frank; Maurer, Marcus.

Affiliation

Hendrix S; Department of Morphology and Biomedical Research Institute, Agoralaan Gebouw D, BE 3590 Diepenbeek, Belgium. sven.hendrix@uhasselt.be

FASEB J ; 27(3): 920-9, 2013 Mar.

Article in En | MEDLINE | ID: mdl-23193170

Subject(s)

Brain Injuries/enzymology; Chymases/metabolism; Mast Cells/enzymology; Nerve Tissue Proteins/metabolism; Serine Endopeptidases/metabolism; Animals; Brain Injuries/genetics; Brain Injuries/pathology; Chymases/antagonists & inhibitors; Chymases/genetics; Inflammation/enzymology; Inflammation/genetics; Inflammation/pathology; Macrophages/metabolism; Macrophages/pathology; Mast Cells/pathology; Mice; Mice, Transgenic; Microglia/metabolism; Microglia/pathology; Nerve Tissue Proteins/genetics; Proto-Oncogene Proteins c-kit/genetics; Proto-Oncogene Proteins c-kit/metabolism; Serine Endopeptidases/genetics; T-Lymphocytes/metabolism; T-Lymphocytes/pathology; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Injuries / Serine Endopeptidases / Chymases / Mast Cells / Nerve Tissue Proteins Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2013 Document type: Article Affiliation country: Belgium

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