Effects of urea on selectivity and protein-ligand interactions in multimodal cation exchange chromatography.

Holstein, Melissa A; Parimal, Siddharth; McCallum, Scott A; Cramer, Steven M

Holstein, Melissa A; Parimal, Siddharth; McCallum, Scott A; Cramer, Steven M.

Affiliation

Holstein MA; Howard P. Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, United States.

Langmuir ; 29(1): 158-67, 2013 Jan 08.

Article in En | MEDLINE | ID: mdl-23199297

Subject(s)

Molecular Dynamics Simulation; Proteins/chemistry; Urea/chemistry; Chromatography, Ion Exchange; Humans; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Protein Binding; Proteins/drug effects; Proteins/metabolism; Ubiquitin/chemistry; Ubiquitin/metabolism; Urea/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urea / Proteins / Molecular Dynamics Simulation Type of study: Prognostic_studies Limits: Humans Language: En Journal: Langmuir Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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