Viability screen on pediatric low grade glioma cell lines unveils a novel anti-cancer drug of the steroid biosynthesis inhibitor family.

Ajeawung, Norbert Fonya; Maltais, René; Jones, Chris; Poirier, Donald; Kamnasaran, Deepak

Ajeawung, Norbert Fonya; Maltais, René; Jones, Chris; Poirier, Donald; Kamnasaran, Deepak.

Affiliation

Ajeawung NF; Pediatrics Research Unit, CHUQ (CHUL), Research Centre, Québec, QC, Canada G1V 4G2.

Cancer Lett ; 330(1): 96-105, 2013 Mar 01.

Article in En | MEDLINE | ID: mdl-23201138

Subject(s)

17-Hydroxysteroid Dehydrogenases/antagonists & inhibitors; Brain Neoplasms/drug therapy; Glioma/drug therapy; Steroids/antagonists & inhibitors; 17-Hydroxysteroid Dehydrogenases/metabolism; Brain Neoplasms/metabolism; Brain Neoplasms/pathology; Cell Growth Processes/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Child; Drug Screening Assays, Antitumor; Glioma/metabolism; Glioma/pathology; Humans; Neoplasm Grading; Steroids/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Steroids / Brain Neoplasms / Glioma / 17-Hydroxysteroid Dehydrogenases Type of study: Prognostic_studies Limits: Child / Humans Language: En Journal: Cancer Lett Year: 2013 Document type: Article Country of publication: Ireland

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