Association between CCL2 haplotypes and knee osteoarthritis.
Int J Immunogenet
; 40(4): 280-3, 2013 Aug.
Article
in En
| MEDLINE
| ID: mdl-23211090
ABSTRACT
We examined five single nucleotide polymorphisms (SNPs) and reconstructed 5-locus haplotypes of the CCL2 gene, in knee osteoarthritis (OA) cases and in controls. The CCL2 rs2857657 variant (G) allele was observed more frequently in female knee OA cases than in controls. One haplotype (H5) was observed exclusively in the control group (f = 2.3%). Genetic variation in the CCL2 gene may be associated with knee OA.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chemokine CCL2
/
Osteoarthritis, Knee
Type of study:
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Int J Immunogenet
Journal subject:
ALERGIA E IMUNOLOGIA
/
GENETICA
Year:
2013
Document type:
Article
Affiliation country:
United kingdom