Structural studies of an immunostimulating gluco-arabinan from seeds of Caesalpinia bonduc.
Carbohydr Polym
; 92(1): 704-11, 2013 Jan 30.
Article
in En
| MEDLINE
| ID: mdl-23218357
ABSTRACT
A water-soluble gluco-arabinan (PS-II, M(W)â¼62 kDa) isolated from the alkaline extract of the endosperm of Caesalpinia bonduc showed the presence of T-Glcp, (1â4)-Glcp, (1â2,3)-Glcp, T-Araf, (1â5)-Araf, (1â2,5)-Araf, and (1â2,3,5)-Araf in a relative proportion of approximately 2223211. The proposed repeating unit of the polysaccharide possessed a branched backbone of two (1â3)-α-D-glucopyranose followed by four (1â5)-α-L-arabinofuranose residues. In case of two (1â3)-α-D-glucopyranose, branching occurs at O-2 by a same residue terminated by another one at O-4 position. Out of four (1â5)-α-l-arabinofuranose residues, one residue is terminated at O-2 and O-3 by two arabinofuranose residues and another one situated at the adjacent position is terminated at O-2 with same residue, and two (1â5)-α-L-arabinofuranose residues are free from branching and located before and after the two branched arabinofuranose residues. This gluco-arabinan molecule and previously reported arabinan showed similar extent of splenocytes and thymocytes stimulation, but arabinan showed appreciable macrophage activations.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polysaccharides
/
Seeds
/
Thymocytes
Limits:
Animals
Language:
En
Journal:
Carbohydr Polym
Year:
2013
Document type:
Article
Affiliation country:
India