Chronic Tempol treatment restores pharmacological preconditioning in the senescent rat heart.

Zhu, Jiang; Rebecchi, Mario J; Wang, Qiang; Glass, Peter S A; Brink, Peter R; Liu, Lixin

Zhu, Jiang; Rebecchi, Mario J; Wang, Qiang; Glass, Peter S A; Brink, Peter R; Liu, Lixin.

Affiliation

Zhu J; Department of Anesthesiology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.

Am J Physiol Heart Circ Physiol ; 304(5): H649-59, 2013 Mar 01.

Article in En | MEDLINE | ID: mdl-23275621

Subject(s)

Aging/metabolism; Antioxidants/pharmacology; Cyclic N-Oxides/pharmacology; Ischemic Preconditioning, Myocardial/methods; Myocardial Ischemia/drug therapy; Myocardium/metabolism; Animals; Calcium/pharmacokinetics; Cardiotonic Agents/pharmacology; Heart/drug effects; Heart/physiology; Hemodynamics/physiology; Male; Mitochondria/drug effects; Mitochondria/metabolism; Myocardial Infarction/drug therapy; Myocardial Infarction/metabolism; Myocardial Infarction/pathology; Myocardial Ischemia/metabolism; Myocardial Ischemia/pathology; Myocardium/pathology; Myocytes, Cardiac/drug effects; Myocytes, Cardiac/metabolism; Myocytes, Cardiac/pathology; Oxidative Stress/drug effects; Oxidative Stress/physiology; Rats; Rats, Inbred F344; Spin Labels; Superoxide Dismutase/metabolism; Tyrosine/analogs & derivatives; Tyrosine/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / Myocardial Ischemia / Ischemic Preconditioning, Myocardial / Cyclic N-Oxides / Myocardium / Antioxidants Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2013 Document type: Article Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google