Fucus/chemistry; Immunologic Factors/administration & dosage; Killer Cells, Natural/drug effects; Laminaria/chemistry; Polysaccharides/administration & dosage; Spleen/drug effects; T-Lymphocytes/drug effects; Animals; Cell Proliferation/drug effects; Coculture Techniques; Cytotoxicity Tests, Immunologic; Humans; Immunity, Innate/drug effects; Immunologic Factors/chemistry; Immunologic Factors/isolation & purification; Injections, Intraperitoneal; K562 Cells; Killer Cells, Natural/cytology; Killer Cells, Natural/immunology; Lymphocyte Activation/drug effects; Mice; Mice, Inbred CBA; Polysaccharides/chemistry; Polysaccharides/isolation & purification; Spleen/cytology; Spleen/immunology; Structure-Activity Relationship; T-Lymphocytes/cytology; T-Lymphocytes/immunology