A CHO cell line engineered to express XBP1 and ERO1-L&#945; has increased levels of transient protein expression.

Cain, Katharine; Peters, Shirley; Hailu, Hanna; Sweeney, Bernie; Stephens, Paul; Heads, James; Sarkar, Kaushik; Ventom, Andy; Page, Catherine; Dickson, Alan

A CHO cell line engineered to express XBP1 and ERO1-Lα has increased levels of transient protein expression.

Cain, Katharine; Peters, Shirley; Hailu, Hanna; Sweeney, Bernie; Stephens, Paul; Heads, James; Sarkar, Kaushik; Ventom, Andy; Page, Catherine; Dickson, Alan.

Affiliation

Cain K; Protein Expression and Purification Group, UCB, Slough, Berkshire, SL1 4EN, England. Katharine.Cain@UCB.com

Biotechnol Prog ; 29(3): 697-706, 2013.

Article in En | MEDLINE | ID: mdl-23335490

Subject(s)

Antibodies, Monoclonal/biosynthesis; DNA-Binding Proteins/genetics; Membrane Glycoproteins/genetics; Oxidoreductases/genetics; Transcription Factors/genetics; Animals; Antibodies, Monoclonal/analysis; Antibodies, Monoclonal/metabolism; CHO Cells; Cell Proliferation; Cricetinae; Cricetulus; Culture Media; DNA-Binding Proteins/biosynthesis; Humans; Membrane Glycoproteins/biosynthesis; Oxidoreductases/biosynthesis; Recombinant Proteins/analysis; Recombinant Proteins/biosynthesis; Recombinant Proteins/metabolism; Regulatory Factor X Transcription Factors; Transcription Factors/biosynthesis; X-Box Binding Protein 1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases / Transcription Factors / Membrane Glycoproteins / DNA-Binding Proteins / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: Biotechnol Prog Journal subject: BIOTECNOLOGIA Year: 2013 Document type: Article Affiliation country: United kingdom

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