Variation in genes in the endothelin pathway and endothelium-dependent and endothelium-independent vasodilation in an elderly population.

Lind, L; Syvänen, A-C; Axelsson, T; Lundmark, P; Hägg, S; Larsson, A

Lind, L; Syvänen, A-C; Axelsson, T; Lundmark, P; Hägg, S; Larsson, A.

Affiliation

Lind L; Department of Medical Sciences, Uppsala University, Stockholm, Sweden. lars.lind@medsci.uu.se

Acta Physiol (Oxf) ; 208(1): 88-94, 2013 May.

Article in En | MEDLINE | ID: mdl-23336501

Subject(s)

Aging/genetics; Brachial Artery/metabolism; Endothelin-1/blood; Endothelin-1/genetics; Endothelium, Vascular/metabolism; Forearm/blood supply; Polymorphism, Single Nucleotide; Vasodilation/genetics; Age Factors; Aged; Aging/blood; Aspartic Acid Endopeptidases/genetics; Brachial Artery/diagnostic imaging; Brachial Artery/drug effects; Endothelin-Converting Enzymes; Endothelium, Vascular/drug effects; Female; Genotype; Humans; Infusions, Intra-Arterial; Linear Models; Male; Metalloendopeptidases/genetics; Phenotype; Prospective Studies; Receptor, Endothelin A/genetics; Receptor, Endothelin B/genetics; Regional Blood Flow; Sweden; Ultrasonography; Vasodilation/drug effects; Vasodilator Agents/administration & dosage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vasodilation / Brachial Artery / Aging / Endothelium, Vascular / Endothelin-1 / Polymorphism, Single Nucleotide / Forearm Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male Country/Region as subject: Europa Language: En Journal: Acta Physiol (Oxf) Journal subject: FISIOLOGIA Year: 2013 Document type: Article Affiliation country: Sweden Country of publication: United kingdom

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