The influence of rosuvastatin on liver microsomal CYP2C6 in hereditary hypertriglyceridemic rat.

Vecera, Rostislav; Zacharová, Alice; Siller, Michal; Matuskova, Zuzana; Skottová, Nina; Anzenbacherová, Eva; Anzenbacher, Pavel

Vecera, Rostislav; Zacharová, Alice; Siller, Michal; Matuskova, Zuzana; Skottová, Nina; Anzenbacherová, Eva; Anzenbacher, Pavel.

Affiliation

Vecera R; Department of Pharmacology, Palacky University Olomouc, Czech Republic. vecera@seznam.cz

Neuro Endocrinol Lett ; 33 Suppl 3: 48-52, 2012.

Article in En | MEDLINE | ID: mdl-23353843

Subject(s)

Fluorobenzenes/pharmacology; Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacology; Hyperlipoproteinemia Type IV/drug therapy; Pyrimidines/pharmacology; Steroid 21-Hydroxylase/antagonists & inhibitors; Sulfonamides/pharmacology; Animals; Aryl Hydrocarbon Hydroxylases/antagonists & inhibitors; Aryl Hydrocarbon Hydroxylases/metabolism; Cholesterol, Dietary/pharmacology; Cytochrome P-450 CYP2C9; Cytochrome P450 Family 2; Gene Expression Regulation, Enzymologic/drug effects; Humans; Hyperlipoproteinemia Type IV/genetics; Hyperlipoproteinemia Type IV/metabolism; Male; Microsomes, Liver/drug effects; Microsomes, Liver/enzymology; RNA, Messenger/metabolism; Rats; Rats, Mutant Strains; Rats, Wistar; Rosuvastatin Calcium; Steroid 21-Hydroxylase/genetics; Steroid 21-Hydroxylase/metabolism; Transcription, Genetic/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Sulfonamides / Steroid 21-Hydroxylase / Hydroxymethylglutaryl-CoA Reductase Inhibitors / Fluorobenzenes / Hyperlipoproteinemia Type IV Limits: Animals / Humans / Male Language: En Journal: Neuro Endocrinol Lett Year: 2012 Document type: Article Affiliation country: Czech Republic Country of publication: Sweden

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