Intermittent access ethanol consumption dysregulates CRF function in the hypothalamus and is attenuated by the CRF-R1 antagonist, CP-376395.

Simms, Jeffrey A; Nielsen, Carsten K; Li, Rui; Bartlett, Selena E

Simms, Jeffrey A; Nielsen, Carsten K; Li, Rui; Bartlett, Selena E.

Affiliation

Simms JA; Ernest Gallo Clinic and Research Center, Department of Neurology, University of California San Francisco, Emeryville, CA, USA.

Addict Biol ; 19(4): 606-11, 2014 Jul.

Article in En | MEDLINE | ID: mdl-23362976

Subject(s)

Alcohol Drinking/physiopathology; Aminopyridines/pharmacology; Central Nervous System Depressants/pharmacology; Corticotropin-Releasing Hormone/drug effects; Ethanol/pharmacology; Hypothalamus/physiopathology; Analysis of Variance; Animals; Central Nervous System Depressants/administration & dosage; Ethanol/administration & dosage; Hypothalamus/drug effects; Male; Models, Animal; Rats; Rats, Long-Evans

Key words

CP-376395; CRF; ethanol; hypothalamus; intermittent access

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alcohol Drinking / Corticotropin-Releasing Hormone / Central Nervous System Depressants / Ethanol / Aminopyridines / Hypothalamus Type of study: Prognostic_studies Limits: Animals Language: En Journal: Addict Biol Journal subject: TRANSTORNOS RELACIONADOS COM SUBSTANCIAS Year: 2014 Document type: Article Affiliation country: United States Country of publication: United States

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