Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1&#945;.

Cárdeno, Ana; Sánchez-Hidalgo, Marina; Rosillo, M Angeles; Alarcón de la Lastra, Catalina

Oleuropein, a secoiridoid derived from olive tree, inhibits the proliferation of human colorectal cancer cell through downregulation of HIF-1α.

Cárdeno, Ana; Sánchez-Hidalgo, Marina; Rosillo, M Angeles; Alarcón de la Lastra, Catalina.

Affiliation

Cárdeno A; Department of Pharmacology, Faculty of Pharmacy, University of Seville, Seville, Spain.

Nutr Cancer ; 65(1): 147-56, 2013.

Article in En | MEDLINE | ID: mdl-23368925

Subject(s)

Antineoplastic Agents, Phytogenic/pharmacology; Colorectal Neoplasms/drug therapy; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Olea/chemistry; Pyrans/pharmacology; Apoptosis/drug effects; Cell Cycle/drug effects; Cell Proliferation/drug effects; Colorectal Neoplasms/metabolism; Colorectal Neoplasms/pathology; Down-Regulation/drug effects; HT29 Cells/drug effects; Humans; I-kappa B Proteins/metabolism; Iridoid Glucosides; Iridoids; NF-KappaB Inhibitor alpha; NF-kappa B/metabolism; PPAR gamma/metabolism; Phenylethyl Alcohol/analogs & derivatives; Phenylethyl Alcohol/pharmacology; Tumor Suppressor Protein p53/metabolism; p38 Mitogen-Activated Protein Kinases/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrans / Colorectal Neoplasms / Olea / Hypoxia-Inducible Factor 1, alpha Subunit / Antineoplastic Agents, Phytogenic Limits: Humans Language: En Journal: Nutr Cancer Year: 2013 Document type: Article Affiliation country: Spain Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google