Using overlap volume histogram and IMRT plan data to guide and automate VMAT planning: a head-and-neck case study.
Med Phys
; 40(2): 021714, 2013 Feb.
Article
in En
| MEDLINE
| ID: mdl-23387737
ABSTRACT
PURPOSE:
To investigate whether an overlap volume histogram (OVH)-driven planning application using an intensity-modulated radiation therapy (IMRT) database can guide and automate volumetric-modulated arc therapy (VMAT) planning for head-and-neck cancer.METHODS:
Based on comparable head-and-neck dosimetric results between planner-generated VMAT and IMRT plans, an inhouse developed, OVH-driven automated planning application containing a database of prior clinical head-and-neck IMRT plans is built into Pinnacle(3) SmartArc for VMAT planning. Double-arc VMAT plans of four oropharynx, four nasopharynx, and four larynx patients are generated and compared with corresponding clinical IMRT plans.RESULTS:
Each VMAT plan is automatically generated in two optimization rounds, while the average number of optimization rounds in generating a clinical IMRT plan is 43. In VMAT plans, statistical superiority (p < 0.01) in sparing of the cord+4 mm, brainstem, brachial plexus, larynx, and inner ear is observed with a slight degradation in low-dose-level planning target volume (PTV) coverage. On average, D(0.1 cc) to the cord+4 mm, brainstem and brachial plexus is reduced by 3.7, 4.9, and 1.6 Gy, respectively; V(50 Gy) to the larynx is reduced by 5.3%; mean dose to the inner ear is reduced by 4.4 Gy; V(95) of low-dose-level PTV coverage is reduced by 0.3% with p = 0.25.CONCLUSIONS:
IMRT-data-driven VMAT planning offers a potential method for generating VMAT plans that are comparable to IMRT plans in terms of dosimetric quality.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Radiotherapy Planning, Computer-Assisted
/
Tumor Burden
/
Radiotherapy, Intensity-Modulated
/
Head and Neck Neoplasms
Type of study:
Etiology_studies
Limits:
Humans
Language:
En
Journal:
Med Phys
Year:
2013
Document type:
Article
Affiliation country:
United States