cRGD peptide-conjugated icosahedral closo-B12(2-) core carrying multiple Gd3+-DOTA chelates for &#945;(v)ß3 integrin-targeted tumor imaging (MRI).

Goswami, Lalit N; Ma, Lixin; Cai, Quanyu; Sarma, Saurav J; Jalisatgi, Satish S; Hawthorne, M Frederick

cRGD peptide-conjugated icosahedral closo-B12(2-) core carrying multiple Gd3+-DOTA chelates for α(v)ß3 integrin-targeted tumor imaging (MRI).

Goswami, Lalit N; Ma, Lixin; Cai, Quanyu; Sarma, Saurav J; Jalisatgi, Satish S; Hawthorne, M Frederick.

Affiliation

Goswami LN; International Institute of Nano and Molecular Medicine, School of Medicine, University of Missouri, Columbia, Missouri 65211-3450, United States.

Inorg Chem ; 52(4): 1701-9, 2013 Feb 18.

Article in En | MEDLINE | ID: mdl-23391150

Subject(s)

Chelating Agents; Contrast Media; Integrin alphaVbeta3/chemistry; Magnetic Resonance Imaging; Neoplasms, Experimental/diagnosis; Prostatic Neoplasms/diagnosis; Animals; Cell Line, Tumor; Chelating Agents/chemical synthesis; Chelating Agents/chemistry; Contrast Media/chemical synthesis; Contrast Media/chemistry; Gadolinium/chemistry; Heterocyclic Compounds, 1-Ring/chemistry; Humans; Integrin alphaVbeta3/biosynthesis; Male; Mice; Mice, SCID; Molecular Structure; Peptides, Cyclic/chemistry; Vitamin B 12/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Magnetic Resonance Imaging / Chelating Agents / Contrast Media / Integrin alphaVbeta3 / Neoplasms, Experimental Limits: Animals / Humans / Male Language: En Journal: Inorg Chem Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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