Effect of taurine feeding on bone mineral density and bone markers in rats.
Adv Exp Med Biol
; 776: 51-8, 2013.
Article
in En
| MEDLINE
| ID: mdl-23392870
ABSTRACT
The purpose of this study was to investigate the effect of dietary taurine supplementation on bone mineral density (BMD) and bone mineral content (BMC) in rats. Twenty Sprague-Dawley male rats (body weight 200 ± 10 g) were divided into two groups, control and taurine group (2% taurine-supplemented diet). All rats were fed on experimental diet and deionized water and libitum for 6 weeks. Serum alkaline phosphatase (ALP) activity, osteocalcin, PTH, and urinary deoxypyridinoline cross-links value were measured as markers of bone formation and resorption. BMD and BMC were measured using PIXImus (GE Lunar Co., Wisconsin) in spine and femur. The effect of diet on ALP, osteocalcine, and PTH was not significant. There were no significant differences in ALP, osteocalcine, and PTH concentration. Urinary calcium excretion was lower in taurine group than in control group. Femur BMC/weight of taurine group was significantly higher than control group. The results of this study showed the possible role of taurine in bone metabolism in male rats.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Taurine
/
Bone and Bones
/
Biomarkers
/
Bone Density
/
Feeding Behavior
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Adv Exp Med Biol
Year:
2013
Document type:
Article
Affiliation country:
South Korea