[Stevens-Johnson syndrome concurrent with primary Epstein-Barr virus infection]. / Syndrome de Stevens-Johnson au cours d'une primo-infection par le virus d'Epstein-Barr.
Ann Dermatol Venereol
; 140(2): 112-5, 2013 Feb.
Article
in Fr
| MEDLINE
| ID: mdl-23395492
ABSTRACT
BACKGROUND:
Primary EBV infection mainly affects children and young adults. Most patients present the characteristic triad of fever, pharyngitis and lymphadenopathy. Symptoms may include a morbilliform eruption, occasionally induced by amoxicillin. We report a case of Stevens-Johnson syndrome concurrent with EBV infection. CASE REPORT A 17-year-old boy consulted for an eruption suggestive of Stevens-Johnson syndrome, which was supported by the histopathology results. The patient had taken no medication during the previous weeks. Laboratory examinations showed atypical activated T lymphocytes. Serological tests and PCR results confirmed the diagnosis of primary EBV infection. The outcome was spontaneously favorable with only symptomatic treatment being required.DISCUSSION:
Stevens-Johnson syndrome is characterized by "target" lesions and profuse mucous membrane involvement. Stevens-Johnson syndrome is frequently drug-induced, being due less frequently to infections. Stevens-Johnson syndrome is very rarely a manifestation of infectious mononucleosis, with only one case being reported in the literature. When confronted with Stevens-Johnson syndrome without any imputable medication, complete screening for infection should be performed, in particular for primary EBV infection.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stevens-Johnson Syndrome
/
Infectious Mononucleosis
Limits:
Adolescent
/
Humans
/
Male
Language:
Fr
Journal:
Ann Dermatol Venereol
Year:
2013
Document type:
Article
Affiliation country:
France