c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis.

Cottle, Denny L; Kretzschmar, Kai; Schweiger, Pawel J; Quist, Sven R; Gollnick, Harald P; Natsuga, Ken; Aoyagi, Satoru; Watt, Fiona M

Cottle, Denny L; Kretzschmar, Kai; Schweiger, Pawel J; Quist, Sven R; Gollnick, Harald P; Natsuga, Ken; Aoyagi, Satoru; Watt, Fiona M.

Affiliation

Cottle DL; Wellcome Trust-Medical Research Council Stem Cell Institute SCI, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.

Cell Rep ; 3(2): 427-41, 2013 Feb 21.

Article in En | MEDLINE | ID: mdl-23403291

Subject(s)

Proto-Oncogene Proteins c-myc/metabolism; Receptors, Androgen/metabolism; Sebaceous Glands/metabolism; Tumor Suppressor Protein p53/metabolism; Animals; Antineoplastic Agents/pharmacology; Cell Differentiation/drug effects; Cells, Cultured; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Proto-Oncogene Proteins c-myc/genetics; RNA, Messenger/metabolism; Receptors, Androgen/genetics; Sebaceous Gland Neoplasms/metabolism; Sebaceous Gland Neoplasms/pathology; Sebaceous Glands/cytology; Signal Transduction/drug effects; Tamoxifen/analogs & derivatives; Tamoxifen/pharmacology; Testosterone/pharmacology; Tumor Suppressor Protein p53/deficiency; Tumor Suppressor Protein p53/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sebaceous Glands / Receptors, Androgen / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-myc Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2013 Document type: Article Affiliation country: United kingdom

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