Exposure of chlorpromazine to 266 nm laser beam generates new species with antibacterial properties: contributions to development of a new process for drug discovery.

Pascu, Mihail Lucian; Danko, Balazs; Martins, Ana; Jedlinszki, Nikoletta; Alexandru, Tatiana; Nastasa, Viorel; Boni, Mihai; Militaru, Andra; Andrei, Ionut Relu; Staicu, Angela; Hunyadi, Attila; Fanning, Seamus; Amaral, Leonard

Pascu, Mihail Lucian; Danko, Balazs; Martins, Ana; Jedlinszki, Nikoletta; Alexandru, Tatiana; Nastasa, Viorel; Boni, Mihai; Militaru, Andra; Andrei, Ionut Relu; Staicu, Angela; Hunyadi, Attila; Fanning, Seamus; Amaral, Leonard.

Affiliation

Pascu ML; Laser Department, National Institute for Laser, Plasma and Radiation Physics, Magurele/Ilfov, Romania. mihai.pascu@inflpr.ro

PLoS One ; 8(2): e55767, 2013.

Article in En | MEDLINE | ID: mdl-23405212

Subject(s)

Anti-Bacterial Agents/pharmacology; Chlorpromazine/radiation effects; Dopamine Antagonists/radiation effects; Drug Discovery; Lasers; Staphylococcus aureus/drug effects; Anti-Bacterial Agents/radiation effects; Chlorpromazine/analogs & derivatives; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Microbial Sensitivity Tests; Tandem Mass Spectrometry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Staphylococcus aureus / Chlorpromazine / Dopamine Antagonists / Drug Discovery / Lasers / Anti-Bacterial Agents Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2013 Document type: Article Affiliation country: Romania Country of publication: United States

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