5-Aza-2'-deoxycytidine may  influence the proliferation and apoptosis of cervical cancer cells via  demethylation in a dose- and time-dependent manner.

Yao, T T; Mo, S M; Liu, L Y; Lu, H W; Huang, M L; Lin, Z Q

5-Aza-2'-deoxycytidine may influence the proliferation and apoptosis of cervical cancer cells via demethylation in a dose- and time-dependent manner.

Yao, T T; Mo, S M; Liu, L Y; Lu, H W; Huang, M L; Lin, Z Q.

Affiliation

Yao TT; Department of Gynecological Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, PR China.

Genet Mol Res ; 12(1): 312-8, 2013 Feb 04.

Article in En | MEDLINE | ID: mdl-23408418

Subject(s)

Apoptosis/drug effects; Apoptosis/genetics; Azacitidine/analogs & derivatives; DNA Methylation/drug effects; Uterine Cervical Neoplasms/drug therapy; Uterine Cervical Neoplasms/genetics; Apoptotic Protease-Activating Factor 1/genetics; Azacitidine/pharmacology; Cell Growth Processes/drug effects; Cell Growth Processes/genetics; Cell Line, Tumor; Decitabine; Female; Gene Expression Regulation, Neoplastic/drug effects; HeLa Cells; Humans; Tumor Suppressor Proteins/genetics; Uterine Cervical Neoplasms/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Azacitidine / Uterine Cervical Neoplasms / Apoptosis / DNA Methylation Limits: Female / Humans Language: En Journal: Genet Mol Res Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2013 Document type: Article Country of publication: Brazil

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