Assessment of cisplatin-induced kidney injury using an integrated rodent platform.

Chen, Yafei; Brott, David; Luo, Wenli; Gangl, Eric; Kamendi, Harriet; Barthlow, Herbert; Lengel, David; Fikes, James; Kinter, Lewis; Valentin, Jean-Pierre; Bialecki, Russell

Chen, Yafei; Brott, David; Luo, Wenli; Gangl, Eric; Kamendi, Harriet; Barthlow, Herbert; Lengel, David; Fikes, James; Kinter, Lewis; Valentin, Jean-Pierre; Bialecki, Russell.

Affiliation

Chen Y; Global Safety Assessment, AstraZeneca R&D Waltham, MA 02451, USA.

Toxicol Appl Pharmacol ; 268(3): 352-61, 2013 May 01.

Article in En | MEDLINE | ID: mdl-23415679

Subject(s)

Acute Kidney Injury/chemically induced; Acute Kidney Injury/metabolism; Cisplatin/metabolism; Cisplatin/toxicity; Acute Kidney Injury/pathology; Animals; Blood Urea Nitrogen; Glomerular Filtration Rate/drug effects; Glomerular Filtration Rate/physiology; Glutathione/metabolism; Kidney/drug effects; Kidney/metabolism; Kidney/pathology; Male; Random Allocation; Rats; Rats, Wistar

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cisplatin / Acute Kidney Injury Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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