Actin Cytoskeleton/metabolism; Actins/metabolism; Hypertension/metabolism; Muscle, Smooth, Vascular/metabolism; Vascular Resistance; Vasoconstriction; Actin Cytoskeleton/drug effects; Actin Cytoskeleton/pathology; Animals; Hypertension/pathology; Hypertension/physiopathology; Male; Mesenteric Arteries/metabolism; Mesenteric Arteries/pathology; Mesenteric Arteries/physiopathology; Muscle, Smooth, Vascular/drug effects; Muscle, Smooth, Vascular/pathology; Muscle, Smooth, Vascular/physiopathology; Polymerization; Protein Kinase Inhibitors/pharmacology; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Vascular Resistance/drug effects; Vasoconstriction/drug effects; Vasoconstrictor Agents/pharmacology; cdc42 GTP-Binding Protein/metabolism; rac1 GTP-Binding Protein/antagonists & inhibitors; rac1 GTP-Binding Protein/metabolism; rho GTP-Binding Proteins/metabolism; rho-Associated Kinases/antagonists & inhibitors; rho-Associated Kinases/metabolism

Cytoskeletal remodelling; Hypertension; Microcirculation; Rac-1; Rho-kinase