Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis.

Johansson, Malin E V; Gustafsson, Jenny K; Holmén-Larsson, Jessica; Jabbar, Karolina S; Xia, Lijun; Xu, Hua; Ghishan, Fayez K; Carvalho, Frederic A; Gewirtz, Andrew T; Sjövall, Henrik; Hansson, Gunnar C

Johansson, Malin E V; Gustafsson, Jenny K; Holmén-Larsson, Jessica; Jabbar, Karolina S; Xia, Lijun; Xu, Hua; Ghishan, Fayez K; Carvalho, Frederic A; Gewirtz, Andrew T; Sjövall, Henrik; Hansson, Gunnar C.

Affiliation

Johansson ME; Department of Medical Biochemistry, University of Gothenburg, , Gothenburg, Sweden.

Gut ; 63(2): 281-91, 2014 Feb.

Article in En | MEDLINE | ID: mdl-23426893

Subject(s)

Colitis, Ulcerative/microbiology; Colitis/microbiology; Colon/microbiology; Intestinal Mucosa/microbiology; Mucin-2/metabolism; Mucus/microbiology; Adolescent; Adult; Aged; Animals; Colitis/metabolism; Colitis/pathology; Colitis, Ulcerative/metabolism; Colitis, Ulcerative/pathology; Colon/metabolism; Colon/pathology; Female; Humans; In Situ Hybridization, Fluorescence; Intestinal Mucosa/metabolism; Intestinal Mucosa/pathology; Male; Mice; Middle Aged; Young Adult

Key words

BACTERIAL TRANSLOCATION; MUCINS; MUCOSAL BARRIER; MUCOSAL PATHOLOGY; MUCUS

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Colitis / Colon / Mucin-2 / Intestinal Mucosa / Mucus Limits: Adolescent / Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Gut Year: 2014 Document type: Article Affiliation country: Sweden

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