The identification of novel, high affinity AQP9 inhibitors in an intracellular binding site.

Wacker, Sören J; Aponte-Santamaría, Camilo; Kjellbom, Per; Nielsen, Søren; de Groot, Bert L; Rützler, Michael

Wacker, Sören J; Aponte-Santamaría, Camilo; Kjellbom, Per; Nielsen, Søren; de Groot, Bert L; Rützler, Michael.

Affiliation

Wacker SJ; The Max Planck Institute for Biophysical Chemistry, Computational Biomolecular Dynamics Group, Göttingen, Germany.

Mol Membr Biol ; 30(3): 246-60, 2013 May.

Article in En | MEDLINE | ID: mdl-23448163

Subject(s)

Aquaporins/antagonists & inhibitors; Aquaporins/chemistry; Models, Molecular; Small Molecule Libraries/chemistry; Animals; Aquaporins/genetics; Aquaporins/metabolism; Binding Sites; Cell Line, Tumor; Humans; Mice; Mutagenesis, Site-Directed; Small Molecule Libraries/metabolism; Structural Homology, Protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Models, Molecular / Aquaporins / Small Molecule Libraries Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Membr Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2013 Document type: Article Affiliation country: Germany

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