A new 5α,8α-Epidioxysterol from the soft coral Sinularia gaweli.
Molecules
; 18(3): 2895-903, 2013 Mar 04.
Article
in En
| MEDLINE
| ID: mdl-23459300
ABSTRACT
A new sterol, (22R,23R,24R)-5α,8α-epidioxy-22,23-methylene-24-methyl-cholest-6,9(11)-dien-3ß-ol (1), and two known sterols, (22R,23R,24R)-5α,8α-epidioxy-22,23-methylene-24-methylcholest-6-en-3ß-ol (2) and 24-methylenecholestane-1α,3ß,5α, 6ß,11α-pentol (3), were isolated from the soft coral Sinularia gaweli. The structure of sterol 1 was established by spectroscopic methods and by comparison of the spectral data with those of known analogues. The cytotoxicity of sterols 1-3 towards various tumor cells is reported.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cholesterol Esters
/
Anthozoa
Limits:
Animals
/
Humans
Language:
En
Journal:
Molecules
Journal subject:
BIOLOGIA
Year:
2013
Document type:
Article
Affiliation country:
Taiwan