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Novel SIRT1 mutation linked to autoimmune diabetes in humans.
Hughes, Jing W; Herold, Kevan C.
Affiliation
  • Hughes JW; Departments of Immunobiology and Internal Medicine, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA.
Cell Metab ; 17(3): 311-2, 2013 Mar 05.
Article in En | MEDLINE | ID: mdl-23473025
Sirtuins are best known for their role in aging but also regulate many different biological processes. A study in this issue of Cell Metabolism (Biason-Lauber et al., 2013) now identifies a mutation in human SIRT1 causing a familial form of autoimmune diabetes.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cell Metab Journal subject: METABOLISMO Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cell Metab Journal subject: METABOLISMO Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States