Skp2 deficiency inhibits chemical skin tumorigenesis independent of p27(Kip1) accumulation.

Sistrunk, Christopher; Kim, Sun Hye; Wang, Xian; Lee, Sung Hyun; Kim, Yongbaek; Macias, Everardo; Rodriguez-Puebla, Marcelo L

Sistrunk, Christopher; Kim, Sun Hye; Wang, Xian; Lee, Sung Hyun; Kim, Yongbaek; Macias, Everardo; Rodriguez-Puebla, Marcelo L.

Affiliation

Sistrunk C; Department of Molecular Biomedical Sciences and the Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606, USA.

Am J Pathol ; 182(5): 1854-64, 2013 May.

Article in En | MEDLINE | ID: mdl-23474082

Subject(s)

Carcinogenesis/pathology; Cyclin-Dependent Kinase Inhibitor p27/metabolism; S-Phase Kinase-Associated Proteins/metabolism; Skin Neoplasms/pathology; Animals; Apoptosis; Carcinogenesis/metabolism; Cell Cycle; Epidermis/metabolism; Epidermis/pathology; Gene Deletion; Humans; Kinetics; Mice; Mice, Inbred C57BL; Papilloma/metabolism; Papilloma/pathology; Skin Neoplasms/metabolism; Tumor Suppressor Protein p53/deficiency; Tumor Suppressor Protein p53/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / S-Phase Kinase-Associated Proteins / Cyclin-Dependent Kinase Inhibitor p27 / Carcinogenesis Limits: Animals / Humans Language: En Journal: Am J Pathol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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