Omega-3 fatty acids enhance phagocytosis of Alzheimer's disease-related amyloid-ß42 by human microglia and decrease inflammatory markers.

Hjorth, Erik; Zhu, Mingqin; Toro, Veronica Cortés; Vedin, Inger; Palmblad, Jan; Cederholm, Tommy; Freund-Levi, Yvonne; Faxen-Irving, Gerd; Wahlund, Lars-Olof; Basun, Hans; Eriksdotter, Maria; Schultzberg, Marianne

Hjorth, Erik; Zhu, Mingqin; Toro, Veronica Cortés; Vedin, Inger; Palmblad, Jan; Cederholm, Tommy; Freund-Levi, Yvonne; Faxen-Irving, Gerd; Wahlund, Lars-Olof; Basun, Hans; Eriksdotter, Maria; Schultzberg, Marianne.

Affiliation

Hjorth E; Division of Neurodegeneration, Department of Neurobiology, Care Sciences & Society, Karolinska Institutet, Stockholm, Sweden.

J Alzheimers Dis ; 35(4): 697-713, 2013.

Article in En | MEDLINE | ID: mdl-23481688

Subject(s)

Alzheimer Disease/immunology; Amyloid beta-Peptides/immunology; Fatty Acids, Omega-3/pharmacology; Inflammation/pathology; Microglia/immunology; Peptide Fragments/immunology; Phagocytosis/drug effects; B7-2 Antigen/metabolism; Brain-Derived Neurotrophic Factor/biosynthesis; CD40 Antigens/metabolism; Cell Line; Docosahexaenoic Acids/pharmacology; Eicosapentaenoic Acid/pharmacology; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunohistochemistry; Interleukin-10/metabolism; Interleukin-6/metabolism; Microglia/drug effects; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Phagocytosis / Fatty Acids, Omega-3 / Amyloid beta-Peptides / Microglia / Alzheimer Disease / Inflammation Limits: Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2013 Document type: Article Affiliation country: Sweden Country of publication: Netherlands

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