A promoter polymorphism in human interleukin-32 modulates its expression and influences the risk and the outcome of epithelial cell-derived thyroid carcinoma.

Plantinga, Theo S; Costantini, Irene; Heinhuis, Bas; Huijbers, Angelique; Semango, George; Kusters, Benno; Netea, Mihai G; Hermus, Ad R M M; Smit, Jan W A; Dinarello, Charles A; Joosten, Leo A B; Netea-Maier, Romana T

Plantinga, Theo S; Costantini, Irene; Heinhuis, Bas; Huijbers, Angelique; Semango, George; Kusters, Benno; Netea, Mihai G; Hermus, Ad R M M; Smit, Jan W A; Dinarello, Charles A; Joosten, Leo A B; Netea-Maier, Romana T.

Affiliation

Plantinga TS; Department of Medicine, Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, 6525 GA, The Netherlands.

Carcinogenesis ; 34(7): 1529-35, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23486016

Subject(s)

Epithelial Cells/pathology; Interleukins/genetics; Polymorphism, Genetic; Promoter Regions, Genetic; Thyroid Neoplasms/genetics; Adult; Alleles; Case-Control Studies; Epithelial Cells/metabolism; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Interleukins/metabolism; Iodine Radioisotopes/administration & dosage; Iodine Radioisotopes/therapeutic use; Lipopolysaccharides/immunology; Lipopolysaccharides/pharmacology; Male; Middle Aged; Odds Ratio; Risk Factors; Thyroid Neoplasms/metabolism; Thyroid Neoplasms/pathology; Thyroidectomy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polymorphism, Genetic / Thyroid Neoplasms / Interleukins / Promoter Regions, Genetic / Epithelial Cells Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Carcinogenesis Year: 2013 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom

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