Effect of low doses of cannabidiolic acid and ondansetron on LiCl-induced conditioned gaping (a model of nausea-induced behaviour) in rats.

Rock, E M; Parker, L A

Rock, E M; Parker, L A.

Affiliation

Rock EM; Department of Psychology, University of Guelph, Guelph, ON, Canada.

Br J Pharmacol ; 169(3): 685-92, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23488964

Subject(s)

Antiemetics/administration & dosage; Antineoplastic Agents/adverse effects; Cannabinoids/administration & dosage; Disease Models, Animal; Nausea/prevention & control; Ondansetron/administration & dosage; Serotonin 5-HT3 Receptor Antagonists/administration & dosage; Animals; Antiemetics/antagonists & inhibitors; Antiemetics/therapeutic use; Behavior, Animal/drug effects; Cannabinoids/antagonists & inhibitors; Cannabinoids/therapeutic use; Conditioning, Psychological/drug effects; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Injections, Intraperitoneal; Lithium Chloride; Male; Nausea/chemically induced; Ondansetron/therapeutic use; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A/chemistry; Receptor, Serotonin, 5-HT1A/metabolism; Serotonin 5-HT1 Receptor Antagonists/pharmacology; Serotonin 5-HT3 Receptor Antagonists/therapeutic use; Taste

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cannabinoids / Ondansetron / Disease Models, Animal / Serotonin 5-HT3 Receptor Antagonists / Antiemetics / Nausea / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Pharmacol Year: 2013 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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