Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages.

Osawa, Tsuyoshi; Tsuchida, Rika; Muramatsu, Masashi; Shimamura, Teppei; Wang, Feng; Suehiro, Jun-ichi; Kanki, Yasuharu; Wada, Youichiro; Yuasa, Yasuhito; Aburatani, Hiroyuki; Miyano, Satoru; Minami, Takashi; Kodama, Tatsuhiko; Shibuya, Masabumi

Osawa, Tsuyoshi; Tsuchida, Rika; Muramatsu, Masashi; Shimamura, Teppei; Wang, Feng; Suehiro, Jun-ichi; Kanki, Yasuharu; Wada, Youichiro; Yuasa, Yasuhito; Aburatani, Hiroyuki; Miyano, Satoru; Minami, Takashi; Kodama, Tatsuhiko; Shibuya, Masabumi.

Affiliation

Osawa T; Laboratory for Vascular Biology, Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan. osawa@lsbm.org

Cancer Res ; 73(10): 3019-28, 2013 May 15.

Article in En | MEDLINE | ID: mdl-23492365

Subject(s)

Angiogenesis Inhibitors/therapeutic use; Jumonji Domain-Containing Histone Demethylases/antagonists & inhibitors; Macrophages/drug effects; Neoplasms/drug therapy; Animals; Cell Hypoxia; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Jumonji Domain-Containing Histone Demethylases/physiology; Mice; Mice, Inbred C57BL; Neoplasms/blood supply; Neoplasms/pathology; Neovascularization, Pathologic/etiology; Receptors, Vascular Endothelial Growth Factor/antagonists & inhibitors; Vascular Endothelial Growth Factor A/antagonists & inhibitors

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Angiogenesis Inhibitors / Jumonji Domain-Containing Histone Demethylases / Macrophages / Neoplasms Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2013 Document type: Article Affiliation country: Japan Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google