AKT signalling and mitochondrial pathways are involved in mushroom polysaccharide-induced apoptosis and G1 or S phase arrest in human hepatoma cells.

OuYang, Fengju; Wang, Guibin; Guo, Wei; Zhang, Yuanyuan; Xiang, Wenhua; Zhao, Min

OuYang, Fengju; Wang, Guibin; Guo, Wei; Zhang, Yuanyuan; Xiang, Wenhua; Zhao, Min.

Affiliation

OuYang F; College of Life Sciences, Northeast Forestry University, Harbin 150040, PR China.

Food Chem ; 138(4): 2130-9, 2013 Jun 15.

Article in En | MEDLINE | ID: mdl-23497867

Subject(s)

Agaricales/chemistry; Biological Factors/pharmacology; Carcinoma, Hepatocellular/physiopathology; G1 Phase Cell Cycle Checkpoints/drug effects; Mitochondria/metabolism; Polysaccharides/pharmacology; Proto-Oncogene Proteins c-akt/metabolism; S Phase Cell Cycle Checkpoints/drug effects; Apoptosis/drug effects; Biological Factors/isolation & purification; Carcinoma, Hepatocellular/drug therapy; Carcinoma, Hepatocellular/genetics; Carcinoma, Hepatocellular/metabolism; Cell Cycle Proteins/genetics; Cell Cycle Proteins/metabolism; Cell Line, Tumor; Cell Proliferation/drug effects; Gene Expression Regulation, Neoplastic/drug effects; Humans; Mitochondria/drug effects; Polysaccharides/isolation & purification; Proto-Oncogene Proteins c-akt/genetics; Signal Transduction/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysaccharides / Biological Factors / Carcinoma, Hepatocellular / Agaricales / Proto-Oncogene Proteins c-akt / G1 Phase Cell Cycle Checkpoints / S Phase Cell Cycle Checkpoints / Mitochondria Limits: Humans Language: En Journal: Food Chem Year: 2013 Document type: Article Country of publication: United kingdom

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