Clarithromycin increases linezolid exposure in multidrug-resistant tuberculosis patients.

Bolhuis, Mathieu S; van Altena, Richard; van Soolingen, Dick; de Lange, Wiel C M; Uges, Donald R A; van der Werf, Tjip S; Kosterink, Jos G W; Alffenaar, Jan-Willem C

Bolhuis, Mathieu S; van Altena, Richard; van Soolingen, Dick; de Lange, Wiel C M; Uges, Donald R A; van der Werf, Tjip S; Kosterink, Jos G W; Alffenaar, Jan-Willem C.

Affiliation

Bolhuis MS; University of Groningen, University Medical Centre Groningen, Groningen.

Eur Respir J ; 42(6): 1614-21, 2013 Dec.

Article in En | MEDLINE | ID: mdl-23520311

Subject(s)

Acetamides/pharmacokinetics; Antitubercular Agents/pharmacokinetics; Clarithromycin/pharmacokinetics; Oxazolidinones/pharmacokinetics; Tuberculosis, Multidrug-Resistant/drug therapy; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism; Acetamides/administration & dosage; Adult; Aged; Antitubercular Agents/blood; Area Under Curve; Clarithromycin/administration & dosage; Drug Interactions; Drug Monitoring/methods; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones/administration & dosage; Prospective Studies; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Clarithromycin / Tuberculosis, Multidrug-Resistant / Oxazolidinones / Acetamides / Antitubercular Agents Type of study: Observational_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Eur Respir J Year: 2013 Document type: Article Country of publication: United kingdom

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