Tu-be or not tu-be: that is the question
about serous ovarian carcinogenesis.
Crit Rev Oncol Hematol
; 88(1): 134-43, 2013 Oct.
Article
in En
| MEDLINE
| ID: mdl-23523591
ABSTRACT
Our understanding of the early natural history of epithelial ovarian carcinoma is limited by the access to early lesions as the disease is very often diagnosed at advanced stages. The incessant ovulation theory from the last century that indicated the ovary as the site for the initiation of high-grade serous cancers is contrary to the newly emerging idea that ovarian cancer could arise from the distal fallopian tube. In view of the recent pathological and molecular studies, we propose to discuss the genesis of high-grade serous ovarian cancer.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ovarian Neoplasms
/
Cystadenoma, Serous
Type of study:
Etiology_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Crit Rev Oncol Hematol
Journal subject:
HEMATOLOGIA
/
NEOPLASIAS
Year:
2013
Document type:
Article