Clinical complexity of Leishmania (Viannia) braziliensis infections amongst travelers.
Eur J Dermatol
; 23(2): 218-23, 2013 Apr 01.
Article
in En
| MEDLINE
| ID: mdl-23557633
ABSTRACT
The protozoan parasite Leishmania (Viannia) braziliensis is one of the main causes of cutaneous and mucocutaneous leishmaniasis in South America. Here, we describe three cases of L. (V.) braziliensis infection which were acquired during travelling in Bolivia, Peru or Paraguay and illustrate the phenotypic heterogeneity and therapeutic complexity of the disease. Two patients presented with unusual clinical manifestations, i.e. with prominent regional lymphadenopathy ("bubonic leishmaniasis") and with simultaneously emerged skin and mucosal lesions, respectively. Both patients insufficiently responded to oral treatment with miltefosine; resolution of the lesions was only achieved after a course of intravenous liposomal amphotericin B.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phosphorylcholine
/
Leishmania braziliensis
/
Amphotericin B
/
Leishmaniasis, Cutaneous
/
Antiprotozoal Agents
Limits:
Adult
/
Aged
/
Humans
/
Male
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Eur J Dermatol
Journal subject:
DERMATOLOGIA
Year:
2013
Document type:
Article