Monoclonal antibody self-association, cluster formation, and rheology at high concentrations.

Lilyestrom, Wayne G; Yadav, Sandeep; Shire, Steven J; Scherer, Thomas M

Lilyestrom, Wayne G; Yadav, Sandeep; Shire, Steven J; Scherer, Thomas M.

Affiliation

Lilyestrom WG; Late Stage Pharmaceutical Development, Genentech (a Member of the Roche Group), 1 DNA Way, South San Francisco, California 94080, USA.

J Phys Chem B ; 117(21): 6373-84, 2013 May 30.

Article in En | MEDLINE | ID: mdl-23560896

Subject(s)

Antibodies, Monoclonal/chemistry; Antibodies, Monoclonal/metabolism; Hydrogen-Ion Concentration; Kinetics; Light; Osmolar Concentration; Rheology; Scattering, Radiation; Scattering, Small Angle; Thermodynamics; X-Ray Diffraction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Monoclonal Type of study: Risk_factors_studies Language: En Journal: J Phys Chem B Journal subject: QUIMICA Year: 2013 Document type: Article Affiliation country: United States

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