CoCl2 induces apoptosis through the mitochondria- and death receptor-mediated pathway in the mouse embryonic stem cells.

Lee, Jin-Ha; Choi, Seong-Ho; Baek, Min-Woo; Kim, Mi-Hwa; Kim, Heong-Jun; Kim, Sun-Hun; Oh, Sang-Jin; Park, Hong-Ju; Kim, Won-Jae; Jung, Ji-Yeon

Lee, Jin-Ha; Choi, Seong-Ho; Baek, Min-Woo; Kim, Mi-Hwa; Kim, Heong-Jun; Kim, Sun-Hun; Oh, Sang-Jin; Park, Hong-Ju; Kim, Won-Jae; Jung, Ji-Yeon.

Affiliation

Lee JH; Research Center for Biomineralization Disorder, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, South Korea.

Mol Cell Biochem ; 379(1-2): 133-40, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23568501

Subject(s)

Apoptosis; Cobalt/pharmacology; Embryonic Stem Cells/physiology; Mitochondria/physiology; Receptors, Death Domain/metabolism; Animals; Caspases/metabolism; Cell Hypoxia; Cytochromes c/metabolism; Embryonic Stem Cells/drug effects; Fas Ligand Protein/metabolism; Hypoxia-Inducible Factor 1, alpha Subunit/genetics; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Membrane Potential, Mitochondrial; Mice; Proto-Oncogene Proteins c-bcl-2/metabolism; Reactive Oxygen Species/metabolism; Signal Transduction; Transcriptional Activation; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism; fas Receptor/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cobalt / Apoptosis / Embryonic Stem Cells / Receptors, Death Domain / Mitochondria Limits: Animals Language: En Journal: Mol Cell Biochem Year: 2013 Document type: Article Affiliation country: South Korea Country of publication: Netherlands

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