Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and µ-receptors.

Roncon, Camila M; Biesdorf, Carla; Coimbra, Norberto C; Audi, Elisabeth A; Zangrossi, Hélio; Graeff, Frederico G

Roncon, Camila M; Biesdorf, Carla; Coimbra, Norberto C; Audi, Elisabeth A; Zangrossi, Hélio; Graeff, Frederico G.

Affiliation

Roncon CM; 1Department of Pharmacology and Therapeutics, State University of Maringá, Brazil.

J Psychopharmacol ; 27(12): 1141-8, 2013 Dec.

Article in En | MEDLINE | ID: mdl-23598399

Subject(s)

Anxiety/metabolism; Panic/physiology; Receptor, Serotonin, 5-HT1A/metabolism; Receptors, Opioid, mu/metabolism; Animals; Behavior, Animal/drug effects; Behavior, Animal/physiology; Male; Maze Learning/drug effects; Maze Learning/physiology; Morphine/pharmacology; Naloxone/pharmacology; Neurons/metabolism; Panic Disorder/metabolism; Periaqueductal Gray/metabolism; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A/drug effects; Receptors, Opioid, mu/drug effects; Serotonin/administration & dosage; Serotonin/metabolism; Serotonin Antagonists/pharmacology; Serotonin Receptor Agonists/pharmacology

Key words

5-HT1A receptor; Serotonin; elevated T-maze; endogenous opioid peptides; periaqueductal grey matter; µ-opioid receptor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Anxiety / Panic / Receptors, Opioid, mu / Receptor, Serotonin, 5-HT1A Limits: Animals Language: En Journal: J Psychopharmacol Journal subject: PSICOFARMACOLOGIA Year: 2013 Document type: Article Affiliation country: Brazil Country of publication: United States

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