Redifferentiation and induction of tumor suppressors miR-122 and miR-375 by the PAX8/PPARÎ³ fusion protein inhibits anaplastic thyroid cancer: a novel therapeutic strategy.

Reddi, H V; Driscoll, C B; Madde, P; Milosevic, D; Hurley, R M; McDonough, S J; Hallanger-Johnson, J; McIver, B; Eberhardt, N L

Reddi, H V; Driscoll, C B; Madde, P; Milosevic, D; Hurley, R M; McDonough, S J; Hallanger-Johnson, J; McIver, B; Eberhardt, N L.

Affiliation

Reddi HV; Department of Medicine, Division of Endocrinology, Mayo Clinic & Foundation, Rochester, MN 55905, USA. honey@mayo.edu

Cancer Gene Ther ; 20(5): 267-75, 2013 May.

Article in En | MEDLINE | ID: mdl-23598436

Subject(s)

MicroRNAs/metabolism; Thyroid Neoplasms/metabolism; Thyroid Neoplasms/therapy; Animals; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Female; Humans; Immunohistochemistry; Mice; Mice, Nude; MicroRNAs/genetics; Oncogene Proteins, Fusion; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms/genetics; Transfection; Up-Regulation; Xenograft Model Antitumor Assays

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Neoplasms / MicroRNAs Limits: Animals / Female / Humans Language: En Journal: Cancer Gene Ther Journal subject: GENETICA MEDICA / NEOPLASIAS / TERAPEUTICA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United kingdom

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