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Identification of the fused bicyclic 4-amino-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.
Goto, Taiji; Shiina, Akiko; Yoshino, Toshiharu; Mizukami, Kiyoshi; Hirahara, Kazuki; Suzuki, Osamu; Sogawa, Yoshitaka; Takahashi, Tomoko; Mikkaichi, Tsuyoshi; Nakao, Naoki; Takahashi, Mizuki; Hasegawa, Masashi; Sasaki, Shigeki.
Affiliation
  • Goto T; R&D Division, Daiichi Sankyo Co., Ltd, 1-2-58 Hiromachi, Tokyo 140-8710, Japan. goto.taiji.kt@daiichisankyo.co.jp
Bioorg Med Chem Lett ; 23(11): 3325-8, 2013 Jun 01.
Article in En | MEDLINE | ID: mdl-23602400
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Cyclic S-Oxides / Benzeneacetamides / Cyclic Nucleotide Phosphodiesterases, Type 4 / Phosphodiesterase 4 Inhibitors / Anti-Inflammatory Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2013 Document type: Article Affiliation country: Japan Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Cyclic S-Oxides / Benzeneacetamides / Cyclic Nucleotide Phosphodiesterases, Type 4 / Phosphodiesterase 4 Inhibitors / Anti-Inflammatory Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2013 Document type: Article Affiliation country: Japan Country of publication: United kingdom