Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3.

Beurel, Eléonore; Kaidanovich-Beilin, Oksana; Yeh, Wen-I; Song, Ling; Palomo, Valle; Michalek, Suzanne M; Woodgett, James R; Harrington, Laurie E; Eldar-Finkelman, Hagit; Martinez, Ana; Jope, Richard S

Beurel, Eléonore; Kaidanovich-Beilin, Oksana; Yeh, Wen-I; Song, Ling; Palomo, Valle; Michalek, Suzanne M; Woodgett, James R; Harrington, Laurie E; Eldar-Finkelman, Hagit; Martinez, Ana; Jope, Richard S.

Affiliation

Beurel E; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL 33136, USA. ebeurel@med.miami.edu

J Immunol ; 190(10): 5000-11, 2013 May 15.

Article in En | MEDLINE | ID: mdl-23606540

Subject(s)

Encephalomyelitis, Autoimmune, Experimental/drug therapy; Glycogen Synthase Kinase 3/antagonists & inhibitors; Th1 Cells/metabolism; Th17 Cells/metabolism; Animals; Encephalomyelitis, Autoimmune, Experimental/immunology; Enzyme Activation; Female; Glycogen Synthase Kinase 3/metabolism; Glycogen Synthase Kinase 3 beta; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Oligopeptides/pharmacology; Peptide Fragments; Protein Isoforms/metabolism; STAT1 Transcription Factor/metabolism; Spinal Cord/cytology; Spinal Cord/immunology; Th1 Cells/drug effects; Th1 Cells/immunology; Th17 Cells/drug effects; Th17 Cells/immunology; Thiadiazoles/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Th1 Cells / Glycogen Synthase Kinase 3 / Encephalomyelitis, Autoimmune, Experimental / Th17 Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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