Serum myoglobin, but not lipopolysaccharides, is predictive of AMPH-induced striatal neurotoxicity.

Levi, Mark S; Patton, Ralph E; Hanig, Joseph P; Tranter, Karen M; George, Nysia I; James, Laura P; Davis, Kelly J; Bowyer, John F

Levi, Mark S; Patton, Ralph E; Hanig, Joseph P; Tranter, Karen M; George, Nysia I; James, Laura P; Davis, Kelly J; Bowyer, John F.

Affiliation

Levi MS; Division of Neurotoxicology, National Center for Toxicological Research, U.S. Food & Drug Administration, Jefferson, AR 72079-9502, USA. mark.levi@fda.hhs.gov

Neurotoxicology ; 37: 40-50, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23608161

Subject(s)

Amphetamine; Basal Ganglia/metabolism; Lipopolysaccharides/blood; Myoglobin/blood; Neurotoxicity Syndromes/blood; Animals; Basal Ganglia/pathology; Biomarkers/blood; Body Temperature Regulation; Disease Models, Animal; Dopamine/metabolism; Fever/blood; Fever/etiology; Fever/physiopathology; Hyperthermia, Induced; Kidney/metabolism; Kidney/pathology; Liver/metabolism; Liver/pathology; Male; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Necrosis; Neurotoxicity Syndromes/etiology; Neurotoxicity Syndromes/pathology; Neurotoxicity Syndromes/physiopathology; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Basal Ganglia / Lipopolysaccharides / Neurotoxicity Syndromes / Amphetamine / Myoglobin Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Neurotoxicology Year: 2013 Document type: Article Affiliation country: United States Country of publication: Netherlands

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google