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Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site.
Wang, Zhen; Sapienza, Paul J; Abeysinghe, Thelma; Luzum, Calvin; Lee, Andrew L; Finer-Moore, Janet S; Stroud, Robert M; Kohen, Amnon.
Affiliation
  • Wang Z; Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
J Am Chem Soc ; 135(20): 7583-92, 2013 May 22.
Article in En | MEDLINE | ID: mdl-23611499
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymidylate Synthase / Magnesium Type of study: Prognostic_studies Language: En Journal: J Am Chem Soc Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymidylate Synthase / Magnesium Type of study: Prognostic_studies Language: En Journal: J Am Chem Soc Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States