Effects of Solutol (Kolliphor) and cremophor in polyethylene glycol 400 vehicle formulations in Sprague-Dawley rats and beagle dogs.

Stokes, Alan H; Kemp, Daniel C; Faiola, Brenda; Jordan, Holly L; Merrill, Christine L; Hailey, James R; Brown, Randy E; Bailey, David W

Stokes, Alan H; Kemp, Daniel C; Faiola, Brenda; Jordan, Holly L; Merrill, Christine L; Hailey, James R; Brown, Randy E; Bailey, David W.

Affiliation

Stokes AH; GlaxoSmithKline Research and Development; Safety Assessment, 5 Moore Drive, Research Triangle Park, NC 27709, USA. alan.h.stokes@gsk.com

Int J Toxicol ; 32(3): 189-97, 2013.

Article in En | MEDLINE | ID: mdl-23616145

Subject(s)

Polyethylene Glycols/chemistry; Stearic Acids/toxicity; Animals; Dogs; Female; Male; Polyethylene Glycols/toxicity; Random Allocation; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Stearic Acids/chemistry

Key words

Cremophor; Kolliphor; Solutol; Sprague-Dawley; beagle dogs

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Stearic Acids Limits: Animals Language: En Journal: Int J Toxicol Journal subject: TOXICOLOGIA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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