Selective bisubstrate inhibitors with sub-nanomolar affinity for protein kinase Pim-1.

Ekambaram, Ramesh; Enkvist, Erki; Vaasa, Angela; Kasari, Marje; Raidaru, Gerda; Knapp, Stefan; Uri, Asko

Ekambaram, Ramesh; Enkvist, Erki; Vaasa, Angela; Kasari, Marje; Raidaru, Gerda; Knapp, Stefan; Uri, Asko.

Affiliation

Ekambaram R; Institute of Chemistry, University of Tartu, Tartu, Estonia.

ChemMedChem ; 8(6): 909-13, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23616352

Subject(s)

Nanostructures/chemistry; Protein Kinase Inhibitors/pharmacology; Proto-Oncogene Proteins c-pim-1/antagonists & inhibitors; Dose-Response Relationship, Drug; Molecular Structure; Protein Kinase Inhibitors/chemical synthesis; Protein Kinase Inhibitors/chemistry; Proto-Oncogene Proteins c-pim-1/metabolism; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase Inhibitors / Nanostructures / Proto-Oncogene Proteins c-pim-1 Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2013 Document type: Article Affiliation country: Estonia Country of publication: Germany

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