Sciadopitysin protects osteoblast function via its antioxidant activity in MC3T3-E1 cells.

Suh, Kwang Sik; Lee, Young Soon; Kim, Young Seol; Choi, Eun Mi

Suh, Kwang Sik; Lee, Young Soon; Kim, Young Seol; Choi, Eun Mi.

Affiliation

Suh KS; Research Institute of Endocrinology, Kyung Hee University Hospital, 1, Hoegi-dong, Dongdaemun-gu, Seoul 130-702, Republic of Korea.

Food Chem Toxicol ; 58: 220-7, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23624148

Subject(s)

Antioxidants/pharmacology; Biflavonoids/pharmacology; Osteoblasts/drug effects; 3T3 Cells; Animals; Antimycin A/pharmacology; Cyclic AMP Response Element-Binding Protein/metabolism; Mice; Osteoblasts/cytology; Phosphorylation

Key words

ALP; ATP; CREB; Differentiation; GSH; MC3T3-E1 cells; MMP; MPT; Mitochondrial dysfunction; Oxidative stress; PGC-1α; ROS; Sciadopitysin; TNF-α; adenosine triphosphate; alkaline phosphatase; cAMP-response element-binding protein; mitochondrial membrane potential; mitochondrial permeability transition; peroxisome proliferator-activated receptor gamma coactivator; reactive oxygen species; reduced glutathione; tumor necrosis factor-α

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoblasts / Biflavonoids / Antioxidants Limits: Animals Language: En Journal: Food Chem Toxicol Year: 2013 Document type: Article Country of publication: United kingdom

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