Retinol-binding protein 4 is elevated and is associated with free testosterone and TSH in postmenopausal women.
J Endocrinol Invest
; 36(10): 831-4, 2013 Nov.
Article
in En
| MEDLINE
| ID: mdl-23633638
ABSTRACT
The aim of this study was to understand the relationship of retinol-binding protein 4 (RBP4) with hormonal and biochemical parameters in pre- and postmenopausal women. We included 69 postmenopausal women and 27 regularly menstruating premenopausal women. Postmenopausal women had statistically significantly higher RBP4 levels when compared to premenopausal women. RBP4 levels were negatively associated with free testosterone and positively associated with thyroid stimulating hormone in postmenopausal women. In premenopausal women RBP4 was positively associated with body mass index. RBP4 levels were increased in postmenopausal women. Although the mechanism is not clear, these findings suggest that RBP4 has a role in the regulation of hormonal and metabolic parameters.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Testosterone
/
Biomarkers
/
Premenopause
/
Postmenopause
/
Retinol-Binding Proteins, Plasma
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Middle aged
Language:
En
Journal:
J Endocrinol Invest
Year:
2013
Document type:
Article
Affiliation country:
Turkey