ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors.

Pollak, Julia; Wilken, Matthew S; Ueki, Yumi; Cox, Kristen E; Sullivan, Jane M; Taylor, Russell J; Levine, Edward M; Reh, Thomas A

Pollak, Julia; Wilken, Matthew S; Ueki, Yumi; Cox, Kristen E; Sullivan, Jane M; Taylor, Russell J; Levine, Edward M; Reh, Thomas A.

Affiliation

Pollak J; Department of Biological Structure, University of Washington, Seattle, WA 98195, USA.

Development ; 140(12): 2619-31, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23637330

Subject(s)

Basic Helix-Loop-Helix Transcription Factors/metabolism; Neuroglia/metabolism; Regeneration; Retina/cytology; Retinal Neurons/cytology; Animals; Basic Helix-Loop-Helix Transcription Factors/genetics; Biomarkers/metabolism; Cell Proliferation; Cells, Cultured; Cellular Reprogramming; Chromatin Assembly and Disassembly; Cloning, Molecular; Epidermal Growth Factor/pharmacology; Gene Expression Regulation; HEK293 Cells; Histones/metabolism; Humans; In Vitro Techniques; Lentivirus/genetics; Lentivirus/metabolism; Luminescent Proteins/metabolism; Mice; Mice, Inbred C57BL; Neurogenesis; Neuroglia/cytology; Patch-Clamp Techniques; Retina/metabolism; Retinal Neurons/drug effects; Retinal Neurons/metabolism; Red Fluorescent Protein

Key words

Glia; Müller; Neurogenesis; Regeneration; Reprogramming; Retina

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Regeneration / Retina / Neuroglia / Basic Helix-Loop-Helix Transcription Factors / Retinal Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United kingdom

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